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You seem to be knowledgeable in this matter. I have a question for you. Several years ago, I heard about a theory that these burst-prone "large, lipid-rich plaques" are essentially "band-aids" created for deficiencies in arterial walls. Does that description align with some of the literature you have read on the subject?

Not the op, but I encountered this theory through Dr. Malcolm Kendrick’s blog [1]. I’m only have a basic medical education (studied clinical psychology at a medical university), but I find the theory plausible. Kendrick’s criticism of the currently dominant cholesterol/statin paradigm is definitely worth looking into

1. https://drmalcolmkendrick.org/2016/01/21/what-causes-heart-d...

I have not heard of this particular phrase. It doesn't quite make sense to me off the top of my head; band aid implies they are beneficial, but lipid-rich plaques are not providing structural integrity or protecting against defects. They are harmful sonce they predispose to MI.

It is likely true that they tend to form where there are surface defects; this idea is decades old and a component of Virchow's triad.

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