It doesn't kill it, quite the contrary, rather makes it ubiquitous. If you want another version you just install virtualenv. It's the same with Perl. We use the Perl version shipped with the distribution (openSuSE) and deploy to that. It's older but it's stable and it works. On our dev environment (mac) we have the same version with all of the modules installed in plenv. We also chose a framework with as little deoendencies as possible (Mojolicious). It looks like it was a great choice.