I know for me, I went to my dream college and studied exactly what I wanted to study, yet I couldn’t keep up. I went from getting mostly As in high school to eventually failing out (later to return). I was under immense psychological stress and couldn’t get myself to do basic things. I was always overwhelmed. I couldn’t and still can’t be in social situations when loud music is nearby. I’ve essentially had to reshape my life to work around this. It made me nearly non-functional.
And years later, now that I’ve built my life in a way where it works with my ADD, I can be incredibly productive and imaginative and innovative.