It’s not everything, just like antibiotics weren’t everything, but progress here will mean curing an incredible amount of human suffering.
The book linked below, a late 2015 text on Molecular Neuropharmacology, is fascinating. Every chapter has a mention of inflammation and usually ibuprofen. It’s that important.
Particularly fascinating is the connection with ADHD, Parkinson’s, and Schizophrenia. All of the diseases have something to do with dysregulation of Dopamine. In particular, it seems like Ibuprofen helps with reducing the effects of Dopamine overload, which is essentially what Schizophrenia is. It’s an inflammation of the mind that is somewhat similar to how we now think sugar causes harm/inflammation. Anyway this overload eventually can lead to underload, or Parkinson’s. ADHD individuals are often overloaded as well due to the treatment with stimulant medication (which is good but can be abused).
I’m not kidding when I say there are Nobel prizes being left on the table here right now.
I have no stomach problems unless I drink too much Starbucks coffee over a 3-day period.
I once cracked a rib and my doctor put me on 800 mg ibuprofen twice a day. _All_ pain went away as my swim times dropped steadily - so much so that it was upsetting the swim team's male hierarchy. Each new day I was recovered and invigorated, much to the irritation of my teammates. This went on for a month until the prescription expired. My swim times rose over the next 3 days as swimming became harder and the usual day-to-day pains returned.
Some people say that NSAIDs will prevent you from improving your ability in athletic events but that was not true for me and ibuprofen.
Around 3 years on that regimen so far.
Can’t wait for the science to mature a bit here for better direction. Pain killers (ibuprofen and others) scare the hell out of me now more than ever because they seem like an easy way out (read: temporary solution). And that’s a dark, dark path to tread on.
Inflammation can have chemical roots. It can also be a side effect of infection.
It seems to me that this is why it's so complicated. Correlation does not prove causation. In order to treat conditions associated with inflammation, wecmay need to identify and resolve the things causing the inflammation.