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This is basically how designing ios/osx apps in xCode works. You set a bunch of constraints that are relative to one another. You can also specify what type of screen those constraints will work on (like iphone vs ipad screens) and portrait / landscape.

I find it quite pleasant once you get used to it.

It is (or at least was) all based on Cassowary: https://en.wikipedia.org/wiki/Cassowary_(software)

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