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As somebody whos been working in this field for a bit, both sequencing and microscopy are advancing in very exciting ways. So Its weird to see an article pitting one against the other.

I do wonder how easy/costly it is to compare differences in single cells via sequencing. I realize there are methods for cell isolation using stuff like microfluidics. But a lot of these methods use elements of microscopy.

My sense has always been that next-gen sequencing coupled with superres microscopy is the way forward.

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