I assume you meant to write 'compound meter', in which case yes, absolutely.
> If you see 6/8, it does not imply there are 2 significant beats
It should. If it does not, then you'll be notating a lot of accented notes explicitly in the music to convey to the player exactly what beat formation is.
If these accents are regular, this is a waste/clutter of notation because it's clear you're actually writing a piece in a time other than 6/8. If the accents are irregular, then they are likely either indicating syncopation, or they are completely irregular in which case you're deliberately writing music with a feel that cannot be accurately described by a single time signature, and you should be changing time signatures through the piece as necessary to describe the beat to the player. (Or it cannot be nicely described by the notation in use).
Jacob Collier is an example of a musician who enjoys exploring this kind of music. See for example: https://youtu.be/b78NoobJNEo?t=14m40s onwards. He invented a new terminology for time signatures to accommodate his style of writing.