Just like its predecessors I give it one or two years more max, then it will fade away like they did.
Qt (Qt Desktop) bindings for python are welcome. But, it's not a suitable for a viable replacement for electron. Maybe Qt Quick, but even qt quick has some decisions that can make incredibly uncomfortable to use in large applications.
In fact, Python is at a disadvantage here anyways because it's not async by default.
Threads avoid the need of callbacks/promises/async/await and they're also cheap and performant unless you need to spawn >10k of them, which seems very unlikely in a desktop applications.
Being async by default is an advantage when you need to handle hundreds of thousands of tasks, all of which are mostly waiting on I/O, which is something that can happen on server side applications, and almost never on the desktop.