I have a lot of personal and company information on 2 of my laptops (Windows 7 and a MacBook). This includes bank account information, private keys, passwords and proprietary source code. I'm always paranoid about my laptops being physically stolen while I'm traveling or if my office is robbed. To help put my mind at ease (somewhat), I've been looking into whole-drive encryption. Incase my laptop does get stolen, I can be sure the thief does not get my data.
It looks like there are 2 solutions out there for Windows - TrueCrypt and Microsoft's Bitlocker. I can't use Bitlocker because my laptop doesn't have a TPM chip, which I'm told is required to encrypt the boot volume. TrueCrypt looks like the only option available right now for Windows.
Also, it looks OS X does not have built-in whole-drive encryption like Window's Bitlocker. Luckily TrueCrypt also has support for OS X.
What do you use to protect your data? Are there any pitfalls that I need to be aware of (besides loosing your password)?
As a side note, I do all my picture editing in Gimp. While this is not commom among professional photographers, it contributes in some ways to my landmark style.