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CRISPR (cas9, cpf1 et al), hands down.

What it can do, what it's likely to do, and we're only in the first inning of understanding how to utilize it and manipulate it. I believe vaccines are the only medical discovery/creation that will end up being comparable in impact on humanity. CRISPR will enable us to directly, fully seize control over our evolution (we've obviously been subtly affecting that for thousands of years).

It'll take a process spanning decades for the most remarkable applications to be discovered and commercialized (or otherwise made available for the general population), and it'll be worth the wait. We'll gradually strip countless inherited diseases from the entire human race in the span of a few generations. Breast cancer? 99.7% wiped out. Parkinson's inheritance? Gone. Cystic fibrosis? Gone. The age of antibiotic resistant infections? CRISPR will solve that soon as well. And so on. As with vaccinations, there will be numerous CRISPR therapies/cures/applications that will be extraordinarily cheap, pennies per person, and deployed to all persons on earth (as with vaccines, it'll take decades of gradual generic'ization, initially all therapies will be expensive, then many will become common, and then they'll be globally deployed for pennies per person).

I've always found biology and medicine research to be a great pivot for people in technology and programming because of the similarities in the mindset used when approaching a problem. For example, alot of bio and med research is looking at complex pathways and interconnected systems and seeing how we can go into different points and add, remove, or change things and how we can interfere with these systems in a controlled way. Software engineers have to similar tasks because they work on large interconnected systems as well and understand different protocols. Penetration testers and security experts also fit this comparison well because they have to try different approaches at different points in a system to gain access or control of a system the same way biology and medicine researchers have to find different ways to interfere with a system to develop a new drug to inhibit a pathway or change the expression of certain proteins. I feel as if crisper / cas9 is a great example for this comparison because researchers are still exploring the many different possible things can do with the same way people in technology explore new tech and apply it to new problems.

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