The biggest problem is that OPT is valid for one year, plus 17 months if you're coming from a technical (STEM: Science, Technology, Engineering and Mathematics) degree. So you have about 2.5 years to do something so big that you can transition to something else (EB-5, startup visa?).
Feel free to ask me more, I did lots of research in this area before quitting my job and starting to work full-time for my own business.
Can you employ others too?
Have you researched fundings and VCs and what they think of F1 visas?
Did you start while you were at school?
Have you heard of any success stories?
What is your backup plan? Have you thought of what you'll do if it doesn't work out? When do you think you will bail out ?