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One Codex (YC S14) | San Francisco (SoMa) | Full-time (ONSITE) | https://www.onecodex.com

One Codex is a platform for microbial genomics. We are a technical, experienced (and profitable!) team working on meaningful problems that range from infectious disease diagnostics to outbreak epidemiology to improving our understanding of the microbiome. We work with top researchers, medical institutions, and biotechs, and have processed samples from all seven continents (and space!).

We're currently looking for generalist engineers across multiple positions, including both those who are backend- and frontend-leaning. Our stack includes Python, Rust, and ES6 Javascript, and we write everything from D3 visualizations to low-level bioinformatics algorithms.

Challenges include: (1) developing novel algorithms for analyzing complex microbial communities; (2) working with terabytes of genomic data; (3) building scientifically reproducible analyses suitable for both research and the clinic; and (4) supporting scientists and developers building on our platform with extensible APIs.

We are based in San Francisco and offer a competitive salary, meaningful above-market equity, and the chance to be an early employee in a well-positioned startup. Benefits include full medical, dental, and vision coverage, a flexible vacation policy and relocation assistance if moving to the Bay Area. We're also willing to sponsor a visa for the right candidate. Please apply here: https://onecodex.recruitee.com/o/software-engineer-full-stac...

Hi, not even sure if I should reply to this, but I just thought maybe some advice anonymously would be the right thing to ask for. Codex, sounds like exactly the kind of company I'd like to work for. A small team working on important possibly life changing technology using new technology and in biology no less Which is probably the thing the that fascinates me most after CS even if I'm not as knowledgeable there. The fact you're using a lot of Python and ES6 React definitely helps too.

My problem is I don't feel like I have the skills you'd be looking for now. I graduated this spring with a CS degree from a no name state school. I came out near the top of my class (honestly I might be the top of CS), but I lack experience. I'm just now taking my first internship and while valuable I don't feel like I'm really learning much, I'm the one trying to teach my coworkers what GIT and why it has advantages over RCS, or more worrying how to use prepared statements to avoid SQL injection.

My plan right now, tentative as it is, is to get an additional undergraduate in biotechnology from my university. As I mentioned Biology has always fascinated and I'm at a time in my life where I have both the time and the opportunity to do this without incurring debt, but I'm devoured by doubt. The kind of job I want is almost all in the startup world and they tend not to take a ton of interns. At the same time by specializing I make myself less attractive to other companies that might otherwise take me on as an intern.

I'm open to any opinion, commentary, or advice, but specifically is this a viable path. What would I need to be good candidate for Codex (or frankly it's like) upon graduation?

The listing says nothing about needing to know biology...

Well there were two reasons. I've always have been fascinated by biology, and while not primary, this and just about every other bio company I've seen lists it as a bonus. This one says: "You have a passion for (or are interested in learning about) biology!"

Second though and this is part of why I'm second guessing it acts as a delaying tactic a bit. I started college 2 years early (less impressive when you realize I'm old for my grade and homeschooled), and I wasn't really thinking about career enough then. I feel like were I to graduate now I'd be on a trajectory that would never see my career developing into what I want.

But honestly you bring up a good point. Would I be better off going into the workplace and gaining some experience?

Yes, work experience is way better than another degree. And sure, they have "nice to have" bio experience. But work at a bio-related company for two years, and now you have bio experience... and a real sense of what you really need to know. And maybe then you'll go back to school, or maybe you'll realize you don't need to.

Sorry for the very late reply. My worry is that the type of companies I'd like to work for don't really seem inclined to take me right now.

I used to co-work out of the same office as One Codex, and these folks are the real deal: Thinking through hard, novel problems on the whiteboard, programming on their own as well as in pairs, all while maintaining a super collegial atmosphere. As someone who was a fly on the wall during some of their earlier days, I can't recommend them highly enough!

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