Perhaps he could have given philanthropy a little mention where he suggested investing a tiny bit in startups, for experience, but his genearl advice was, "Do something remarkable." He didn't suggest investing a big chunk of the money in startups, or founding a startup, or anything else.
There are plenty of unremarkable ways to donate money to non-profits. Anyone can start a non-profit. They claim to be benevolent. So does the government. If you donate to some non-profits, you might as well be donating to the government by optimizing for high taxes. He could find someone to advise him to donate to a good organization, so the money doesn't get wasted, but that brings us back to the point about not trusting every financial advisor on the planet.