My resume resembles Swiss cheese. I have a whole bunch of short-term jobs, and holes where I've taken off a year or more to pursue my own ideas (I'm "freelancing" during that time).
Fortunately I was able to get another job after the last break, but I didn't seem to be getting as many callbacks as I'm used to. This, coupled with my age, tells me I need to stay put for a while. And I hate that.
That said, I've been with my current employer for three years now, and I have no intention of leaving, thanks to their flexible work schedule.