I bet that someone's very first experience sleeping in a hotel would yield a poorer quality than their 100th one.
An hotel room is a place where I am supposed to sleep while a decent number of people (the hotel staff + anyone caring to social engineer) has full access to the door key and I rely on an unfamiliar security system to warn me when things go awry (fire, blackout, water leak etc)
The only places I would feel less safe would be a night train or a taxi in the middle of nowhere.
Do you normally sleep in an especially secure room? There seems as much likelihood that a hotel staff member would "break" in to my hotel room as someone would break in to my home. It's marginally easier for staff but then they stand to lose their livelihood, are much more likely to be caught, et cetera.
Do you leave a door propped against the door handle, or a handle alarm, or anything, to mitigate your feelings of exposure?
In Japan it was a door chain, in France you leave the key in the door and it blocks external keying. Also you'll have to pass the building gates before reaching an appartment.
It's not infailable, but it's significantly more protected than any standard hotel room.
More than anything I remember unintentionally screwing hotel keys by having them with other devices, and the hotel front would reprint them pretty easily without asking anything more than the room number and the registered name.
If that's true, I seriously wonder how you ever get in a car.
As a sign of that you wouldn't leave valuable stuff on an hotel room table while you're out, as you would in your house.
Speak for yourself.
I routinely leave my most valuable possession (my laptop) in hotel rooms. I'm not paranoid.
I've been in a hotel where my room had 2 large bolts on the inside of the door in addition to the normal lock. This did nothing for my quality of sleep!