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With Typescript, node is a decent choice as long as you aren't doing anything fancy on the server. I do a lot of data science stuff and I would literally rather bang my head against a wall violently than use javascript for that.

If thats pretty much all your server does then you can use whatever you like - most of the time I'd want the "hard crunching" stuff tucked away way in another service to call.

Unless your hard crunching needs to be distributed to complete in a timely manner, it is much easier to scale up by having a load balancer distribute users across multiple instances of an app.

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