I used to be an organizer for the Green Party so I am capable of very cynical views of the electoral system but also going door to door to get signatures, running candidates, etc.
In local races, even up to the state legislature level, I often know the people involved personally. I've had friends and acquaintances run for local offices as Greens, Democrats and Republicans. I even meet a congressional candidate from time to time.
For the presidential election next year the immediate thing on my mind is that I don't want to see a Hillary Clinton - Jeb Bush matchup because as much as the "Anderson-Horowitz politics" people on HN would find that easy to swallow, it would set a very bad precedent for our country.
I always vote 3rd party when available, because I know they won't win. It's a "none of the above" vote, where "above" means dems and reps.
If I actually like a mainstream candidate I will vote for them. Personally if I was in a "swing state" I might be more inclined to vote for a mainstream candidate but I am in the kind of state Hillary Clinton would go to get herself a solidly democratic constituency so most of the time I vote for whoever I want.
This quote must feel like a punch in the gut to anyone who believes in that 3'rd party you voted for. They thought "look, we didn't win, but at least X number of people agree with us, we'll do better next time". They don't realize you haven't even looked at what they stood for, and it wasn't even a pity vote, it was a throwaway because you didn't feel like writing in Micky Mouse.