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Depends on the medication, dose, and your personal physiology. I was on a low dose dextroamphetamine as needed for a while. Then life got stressful and I found myself getting mild anxiety from it. I switched to Vyvanse which dextro packaged for extended release (lasts for 14 hours). Vyvanse did not induce any jitters but would keep me up late if I didn't take it first thing in the morning. I switched to a different extended release dextro that lasts for about half the time as Vyvanse. That's worked out well because I can take it in the afternoon without jeopardizing my sleep.

As a rule of thumb though I don't take stimulants on a regular basis, just as needed. Don't want to become dependent.

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