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Since when can we reliably test for prions? Could it be that those misfolded proteins have been around forever?



Possibly, but the modern age has considerably more vectors for exposure to these misfolded proteins, and the last statement of what logfromblammo said[0], these misfolding proteins don't always affect core processes of the body.

[0] https://news.ycombinator.com/item?id=11534177




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